NiOS (Non-Invasive Oocyte Sorting) Study
Ovation Fertility
Summary
The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
Description
Introduction Magenta™ is a software image analysis tool developed by Future Fertility that allows personalized reproductive prediction for each oocyte (egg cell) analyzed. It is a cloud-based software that was developed to assess the probability of an oocyte to fertilize and develop into a blastocyst (ball of rapidly dividing cells that will become an embryo). It is a non-invasive image analysis tool that uses artificial intelligence (AI) to predict outcomes based on a single 2-D image of a mature oocyte (denuded oocyte) prior to freezing or sperm injection (ICSI). Magenta™ was designed and bu…
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Fresh MII oocytes * ICSI cycles with patient's or donor's sperm * Patient's or donor's oocytes * Full IVF cycle information available (including total number of oocytes retrieved, total MII oocytes, fertilization, embryo and blastocyst development, as well as ploidy status or implantation results, and 6-7 week ultrasound, if applicable) * Good quality images of MII oocytes taken with a specified camera (Basler) and Future Fertility Software * Single embryo transfers (SETs) at blastocyst stage. * Blastocyst freeze-all cycles Exclusion Criteria: * Severe male factor infe…
Interventions
- OtherMagenta AI image analysis tool
MagentaTM is a non-invasive image analysis tool that utilizes artificial intelligence to evaluate 2-dimensional images of denuded mature MII oocytes. The MagentaTM software has been analyzed retrospectively, by Future Fertility. This data displays that a higher MagentaTM score is associated with a higher chance of blastocyst development. Additionally, the MagentaTM software has been validated in a prospective multi-center study, displaying that a higher MagentaTM score correlates to a higher chance of blastocyst development.
Locations (3)
- Ovation Fertility Las VegasLas Vegas, Nevada
- Ovation Fertility CincinnatiCincinnati, Ohio
- Ovation Fertility - NashvilleNashville, Tennessee