A Randomized Trial of Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

Summary

Participants eligible for the study will be randomly allocated (1:1:1) to receive either Luminopia dichoptic treatment while wearing optical correction if needed, Vivid Vision dichoptic treatment while wearing optical correction if needed, or continued optical correction alone if needed, with clinical assessments at 9- and 18-weeks post-randomization. At the 18-week primary outcome visit, participants who were randomly assigned to receive optical correction alone if needed with an IOD of 1 logMAR line (5 letters) or more, will be offered randomization to Luminopia or Vivid Vision dichoptic therapy and if they accept, followed forward with visits at 27- and 36-weeks post-randomization. The study will end for all other participants at 18 weeks.

Eligibility

Age range

8–12 years

Sex

All

Healthy volunteers

No

Interventions

• Device
  Vivid Vision

  dichoptic video games played through a virtual reality headset

• Device
  Luminopia

  dichoptic movies/shows shown through a virtual reality headset

• Device
  Optical Correction

  Glasses prescribed at investigator discretion

Locations (58)