Comparison of Conventional Clinical and Abbreviated MR Enterography Protocols in Children and Adults With Crohn's Disease
Children's Hospital Medical Center, Cincinnati
Summary
The purpose of our study is to compare an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) protocol to a conventional, standard of care MRE in children and adults with Crohn's Disease.
Description
This multi-center study will evaluate the effectiveness of an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) to document the presence and severity of small bowel inflammation, the presence and features of stricturing and penetrating disease in children and adults with Crohn's Disease. The abbreviated MRI of the bowel or MRE will not involve IV contrast or an injection of glucagon and water will replace the oral contrast used in standard of care MREs. Scan time will be greatly reduced with the abbreviated MRE ( approximately 15 minutes) compa…
Eligibility
- Age range
- 10+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Established Crohn's disease diagnosis in patients 10 and older * Undergoing clinical magnetic resonance enterography (MRE) examinations for any reason(s) below * Staging/ restaging/ follow- up of intestinal inflammation * Evaluation of known or suspected luminal narrowing/ stricturing disease * Evaluation of known or suspected internal penetrating disease Exclusion Criteria: * Undergoing initial imaging for suspected Crohn's disease where the diagnosis of Crohn's disease has yet to be definitively established * New Crohn's disease diagnosis, undergoing baseline…
Interventions
- Diagnostic TestMagnetic Resonance Imaging (MRI) or Magnetic Resonance Enterography (MRE)
Abbreviated magnetic resonance enterography (MRE) imaging to detect active inflammation in patient's with known Crohn's Disease.
Locations (2)
- Mayo ClinicRochester, Minnesota
- NYU LangoneNew York, New York