Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
Loma Linda University
Summary
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes. The main questions it aims to answer are: Does percutaneous cryoablation improve short and long term pain scores? Does percutaneous cryoablation improve short and long term respiratory mechanics? Does percutaneous cryoablation improve long term quality of life? Does percutaneous cryoablation decrease delirium? Researchers will compare cryoablation to standard multimodal pain therapy to see if this impacts respiratory recovery. Participants will undergo randomization, percutaneous cryoablative procedure, and participate in tests at pre-determined intervals to evaluate their pulmonary recovery.
Eligibility
- Age range
- 18–80 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * \> 18 years old * \> 2 rib fractures * Verbal Pain score \> 5 * Incentive Spirometry \< 60% of predicted Exclusion Criteria: * Isolated Fractures of Ribs 1-3 and/or 10-12 * Posterior Rib Fracture \< 4 cm from costovertebral joint * Sternal, Clavicle, Scapula Fracture * Thoracic Spinal Fracture of any type * Open Abdominothoracic Surgery * Unstable Spine * Extensive Subcutaneous Emphysema * BMI \> 35 * Plan for Rib Plating * Chronic Opioid Use * Prior to study enrollment: Intubated, Traumatic Brain Injury, Dementia, Cognitive Impairment, Encephalopathy * Coagulopathy, S…
Interventions
- ProcedurePercutaneous Cryoablation of Intercostal Nerves
Percutaneous Cryoablation of Intercostal Nerves
- OtherMulti-modal pain regimen
Standard rib fracture protocol including cyclooxygenase inhibitors, anti-neuropathic, muscle relaxers, short term anesthesia interventions (percutaneous block, epidural)
Location
- Loma Linda University HealthLoma Linda, California