Establishing Daily Applicable Parameters for Using Magnetic Resonance Spectroscopy of Spinal Cord
M.D. Anderson Cancer Center
Summary
To learn if MRS can effectively assess spinal cord lesions.
Description
Primary Objective: Establish the feasibility and spectrum of MRS for adult patients while mapping the total spine spectrum at short TEs to allow for future comparison with patients to assess spinal cord lesions malignant potential and grade. Secondary Objective: Test success of the spectrum by implementing the protocol on 3 low volume LMD receiving LMD receiving CSI. This will allow us to test reproducibility of the protocol and test effect of radiation on spinal cord at different time frames. This will serve as secondary data for subsequent trials targeting functional statues after radiati…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: Volunteers: * Adults \> 18 years * Healthy with no malignancy, demyelinating disease, back pain, degenerative disease, or spinal cord lesions. * Consent able patients. Patients with low volume LMD to receive treatment CNS radiation: * Adults \> 18 years old. * MR or CSF with evidence of LMD. * Patients to receive CSI as part of standard treatment of LMD disease. * Consent able patients, willingness and ability to comply with the study procedures. * No spinal cord lesions only LMD disease * Recruitment by radiation oncology faculty in consultation with Dr. De. . . Exclu…
Interventions
- Diagnostic TestMagnetic Resonance Spectroscopy (MRS) Scan
Participants will receive MRS Scan
Location
- MD Anderson Cancer CenterHouston, Texas