Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT): Pilot Intervention and Assessment of Barriers and Facilitators of Implementation
Southcentral Foundation
Summary
The purpose of this study is to refine and pilot an intervention using the Nicotine Metabolite Ratio (NMR) to inform the selection of pharmacologic treatment to increase smoking abstinence among Alaska Native and American Indian people. This is a single-arm pilot trial to assess and improve acceptability and feasibility.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: (Patients) * Alaska Native or American Indian person by self-report * eligible for or already receiving services at Southcentral Foundation (SCF) * age 18 years or older * daily smoking in the past 30-days * if other nicotine or tobacco products are used, cigarettes are main product used * planning to schedule an appointment with the Quit Tobacco Program to seek smoking cessation treatment in the next 30 days * willing to make a quit attempt within 30 days of enrollment in the Quit Tobacco Program * willing to have a blood test to inform their treatment * willing to try a…
Interventions
- OtherNicotine Metabolite Ratio
Blood specimens will be drawn, in clinic, by clinical staff trained in blood collection (e.g., certified medical assistant, nurse). Through regular clinic procedures, lab staff will ship for processing to Quest. Quest uses liquid chromatography tandem mass spectrometry with a limit of detection of 2ng/ml for all analytes and will quantify NMR within 3-6 days of sample arrival. Samples will be consumed during testing. Results of NMR will be returned to primary care providers, and NMR-informed medication recommendations will be made to participants.
Location
- Anchorage Native Primary Care CenterAnchorage, Alaska