Journey to Understanding - American Indian Peoples Engagement in Cancer Research Arizona (JUNIPER)
Mayo Clinic
Summary
This clinical trial is studying the genetic changes in cells associated with different types of cancer in American Indian (AI) populations in the Southwest to improve cancer screening, precision prevention, and therapeutic intervention for individual in these communities. AI tribes have much lower rates of cancer screening, have more limited access to healthcare, are more often diagnosed at later stages of disease, and have the poorest outcomes in all types of cancer when compared to any other racial and ethnic group in the United States. Due to these significant cancer health disparities, AIs have been understudied and little is known about the molecular characterization of tumors arising in AIs. Undergoing genetic testing of tumors may improve cancer outcomes in AI participants and communities.
Description
PRIMARY OBJECTIVES: I. To develop culturally appropriate, respectful, trusted, and collaborative means to engage and recruit American Indians (AIs) affected by cancer (newly diagnosed cancer participants, participants undergoing cancer treatment, and cancer survivors) for molecular characterization of their tumors. Ia. Conduct direct participant engagement with cancer participants/survivors, community advisors, and partners to refine and optimize methods/processes. Ib. Identify, recruit, and consent eligible AI cancer participants/survivors. Ic. Implement tissue acquisition, epidemiologic,…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Male or female adults \>= 18 years of age * Cancer patient undergoing active treatment or a cancer survivor * Self-identify as American Indian Exclusion Criteria: * Unable to provide informed consent * Individuals who are under 18 years of age * Prisoners
Interventions
- ProcedureBiospecimen Collection
Undergo blood or saliva, leftover tissue, and mouthwash saliva sample collection
- OtherCommunication Intervention
Receive care plan recommendations
- OtherGenetic Testing
Undergo genetic testing
- OtherSurvey Administration
Ancillary studies
Location
- Mayo Clinic in ArizonaScottsdale, Arizona