Coping Skills Training for Symptom Management and Daily Steps (Step Up)
Duke University
Summary
The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable HCT patients to effectively cope with symptoms (pain, fatigue, and stress) to improve their ability to engage in physical activity that can improve physical disability.
Description
The objective of this R01 project is to use novel mobile health (mHealth) behavioral intervention approaches to enable patients who have undergone hematopoietic stem cell transplant (HCT) and Car T cell therapy to effectively cope with their symptoms to improve their ability to engage in physical activity that can improve physical disability. In a NCI R21 study, we developed a hybrid in-person and mHealth Coping Skills Training for Symptom Management and Daily Steps (Step Up) intervention protocol, including mobile app. Step Up provides HCT and CAR T patients with cognitive behavioral coping s…
Eligibility
- Age range
- 18–99 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * receipt of an autologous (auto) HCT or CAR-T cell therapy due to a hematologic malignancy, such as a diagnosis of leukemia, lymphoma, multiple myeloma * age \>18 * self-reported fatigue, pain, and psychological distress (confirmed at recruitment) - minimum two of three symptoms reported at \>3 on 0-10 scale * life expectancy \> 12 months Exclusion Criteria: * cognitive impairment (e.g., dementia) recorded in the chart or suspected by provider * metastases to the brain * presence of a severe psychiatric condition (e.g., psychotic disorder) that would contraindicate safe…
Interventions
- BehavioralStep Up
A hybrid in-person and mHealth (mobile health) coping skills training and activity coaching intervention.
- OtherUsual Care Plus (UC+)
Usual medical care plus videos delivering educational content via an app.
Location
- Duke Cancer InstituteDurham, North Carolina