The PERSEVERE Study
Inari Medical
Summary
Randomized Controlled Trial of High-Risk Pulmonary Embolism Comparing FlowTriever System vs. Standard of Care
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Age at enrollment ≥18 years 2. Objective evidence of a proximal filling defect in at least one main or lobar pulmonary artery 3. High-risk class of acute PE 4. RV dysfunction, as defined RV/LV ratio ≥1.0 5. Willing and able to provide informed consent, or if unable, through a Legal Authorized Representative, with permitting research without prior consent as a third option (for Europe and UK sites only), provided compliance with IRB/EC approvals and adherence to regulatory, ethical and national standards Exclusion Criteria: 1. Prolonged cardiac arrest with loss of cons…
Interventions
- DeviceFlowTriever System
Mechanical thrombectomy for pulmonary embolism
- ProcedureStandard of Care
Standard of care treatment for pulmonary embolism
Locations (26)
- Yale UniversityNew Haven, Connecticut
- Orlando Health Regional Medical CenterOrlando, Florida
- Sarasota Memorial HospitalSarasota, Florida
- Emory UniversityAtlanta, Georgia
- University of Mississippi Medical CenterJackson, Mississippi
- Northwell HealthBay Shore, New York