Study detail
RecruitingObservational
Characteristics of Gastroesophageal Reflux in Children With Cystic Fibrosis
Duke University
Summary
The purpose of this study is to evaluate the prevalence of gastroesophageal reflux disease (GERD) symptoms in pediatric patients with cystic fibrosis using the Gastroesophageal Symptom Assessment Scale (GSAS) and the impact of stopping anti-GERD therapy on the GERD symptoms reported.
Eligibility
- Age range
- 2–18 years
- Sex
- All
- Healthy volunteers
- No
Detailed criteria
Inclusion Criteria: * Children 2-18 years of age with a confirmed CF diagnosis by either a positive sweat test or 2 disease causing CFTR mutations. * Signed consent Exclusion Criteria: * Declining to participate in the study or sign consent * History of severe GERD per gastroenterology diagnosis and documentation * GSAS score \>80
Interventions
- OtherDiscontinuation of GERD therapy
GERD therapy will be discontinued at time of enrollment.
Location
- Duke University HospitalDurham, North Carolina