University of California, San Diego
Modern intensive care units (ICUs) are increasingly adopting newer modes of mechanical ventilation such as adaptive pressure control (APC) modes but there are limited data available regarding risks and benefits of newer modes versus traditional ventilation modes. APC can inadvertently deliver high tidal volumes, which maybe harmful. High tidal volumes may be unrecognized by the provider, due to the complexities of ventilator algorithms and patient interactions. The objective of this aim is to identify risk factors for excess tidal volumes in patients on adaptive pressure control.
Inclusion Criteria: * Admitted to ICU with acute respiratory failure * On adaptive pressure control mode of ventilation * Tidal volumes set between 5-8 cc/kg ideal body weight Exclusion Criteria: * Current use of neuromuscular blockade * Inability to obtain consent from patient or surrogate decision maker * Treating clinician refusal
Patient lung mechanics and respiratory drive and effort will be measured
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