Sevoflurane/Dexmedetomidine vs. Isoflurane and Their Effects on Pediatric Emergence Delirium
Mayo Clinic
Summary
The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.
Eligibility
- Age range
- 2–7 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Pediatric patients aged 2-7 years. * Surgeries include ENT cases (i.e., tonsillectomy/adenoidectomy), ophthalmology cases (i.e., strabismus), and urology cases. * Can be outpatient or General Care inpatient procedures. * All cases must include an IV and an endotracheal tube (ETT). Exclusion Criteria: * Severe developmental/cognitive delay (unable to make eye contact, nonverbal, or inability to interact with providers for PAED scale assessment requirements) * TIVA cases. * No PIV in place during the case, planned PICU admission postoperatively. * Previous history of sev…
Interventions
- DrugSevoflurane
Subjects will receive standard of care anesthesia Sevoflurane, with intravenous push Dexmedetomidine
- DrugIsoflurane
Subjects will receive standard of care anesthesia Isoflurane
Location
- Mayo Clinic in RochesterRochester, Minnesota