Effect of Different Grafting Material Following Surgically Facilitated Orthodontics Therapy: a Randomized Controlled Clinical Trial
The University of Texas Health Science Center, Houston
Summary
The purpose of this study is to quantitatively investigate the radiographic changes of alveolar bone, and gingival tissue changes of the mandibular anterior teeth in experimental group A receiving SFOT using freeze-dried allograft with a collagen membrane, experimental group B receiving SFOT using particulate xenograft covered by a collagen membrane and control group receiving only orthodontics therapy.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * American Society of Anesthesiologists (ASA) I/II * Periodontal diagnosis of clinical gingival health or gingivitis on intact/reduced periodontium per 2017 American Academy of Periodontology (AAP) classification * No history of periodontitis. * Class I malocclusion * Crowding of 4 mm or less on mandibular anterior incisors * Incisor mandibular plane angle between 90-100 degrees * No extractions indicated as part of the orthodontic treatment plan * Keratinized tissue of at least 3mm Exclusion Criteria: * Patients who are current smokers * Pregnancy * Uncontrolled diabete…
Interventions
- DeviceSurgically facilitated orthodontics therapy (SFOT) using allograft
Participants will receive Surgically facilitated orthodontics therapy (SFOT) along with bone grafting using particulate allograft and collagen membrane, prior to orthodontics treatment.
- DeviceSurgically facilitated orthodontics therapy (SFOT) using xenograft
Participants will receive SFOT using particulate xenograft and collagen membrane, prior to orthodontics treatment.
- DeviceUsual care
Participants will have conventional orthodontics treatment with Invisalign aligners, without any surgical intervention
Location
- The University of Texas Health Science Center at HoustonHouston, Texas