Greater Houston Area Pediatric Bipolar Registry
The University of Texas Health Science Center, Houston
Summary
The purpose of this study is to perform a comprehensive research assessment of children and adolescents who meet The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria for Bipolar Disorder (BD) , offspring of a parent with BD, and healthy controls (HC), to obtain blood samples and saliva samples from each subject to allow the evaluation for BD biomarkers and genetic information, to notify participants about future research studies they may qualify for , to recommend follow-up with an outpatient provider if needed and to use magnetic resonance imaging (MRI) (structural MRI and diffusion tensor imaging) to investigate brain structures and relevant pathways associated with mood and behavioral regulation, conversion from softer forms of the BD spectrum (BD-NOS) to harder forms (BD-I and BD-II) and possible early identification.
Eligibility
- Age range
- 6–17 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria for bipolar patients or offspring of bipolar parents: * Any current mood state (in the case of bipolar subjects) * For bipolar patients: DSM-V criteria for BD type I, BD type II, or BD NOS, as per the administration of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) * For the offspring of bipolar parents: at least one parent meeting DSM-V criteria for BD type I or BD type II, or BD NOS as per the administration of the MINI Adult Exclusion Criteria for bipolar patients or offspring of bipolar parents: * Autism Spectrum Disorder (AS…
Location
- The University of Texas Health Science Center at HoustonHouston, Texas