CogMed Intervention Targeting Working Memory in Patients with Mild Cognitive Impairment
St. Joseph's Hospital and Medical Center, Phoenix
Summary
The purpose of this study is to test whether a special memory training program, called CogMed, can help people with early memory problems. The Investigators want to see if this training improves memory and also helps reduce stress. The Investigators also want to see if CogMed results in changes to a blood biomarker called p-Tau 217, which possibly indicate Alzheimer's disease (AD).
Description
The goal of this study is to conduct a pilot clinical trial aimed at comparing the effects of CogMed intervention plus Treatment As Usual (TAU) versus TAU alone in patients with Mild Cognitive Impairment (MCI). Based on our preliminary data from brain health program, the primary hypothesis is that the CogMed intervention may improve the CogMed measures and possibly working memory. This may improve sense of self-efficacy and lead to a decrease in perceived stress, thereby demonstrating possible transfer of cognitive benefits to biobehavioral construct of perceived stress. Additionally, the stud…
Eligibility
- Age range
- 50+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Male or female outpatients ages ≥ 50 years; 2. Meet Mayo Clinic Criteria for MCI. (Patients with mild cognitive impairment) 3. Access to the internet through computer 4. A proficiency in speaking and reading English or having a family member who is proficient in reading and speaking English and is willing to serve as a translator. 5. Vision and hearing must be sufficient to comply with study procedures. Exclusion Criteria: 1. Mini Mental State Exam (MMSE) score less than 19 or patients diagnosed with moderate or severe dementia by a clinician. 2. In the opinion of the…
Interventions
- OtherCogMed
CogMed which is a computerized working memory training program developed by Karolinska University.
Location
- Barrow Neurological Institute, Division of Alzheimer's DiseasePhoenix, Arizona