Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults (CASCILS)
University of Pittsburgh
Summary
The goal of this study is to learn how cannabis use and discontinuation affect sleep, circadian rhythms, and sensitivity to light. The main questions it aims to answer are: 1. Does cannabis use and discontinuation impact sleep drive? 2. Does cannabis use and discontinuation impact light sensitivity and circadian phase?
Description
Researchers will compare sleep, circadian phase, and light sensitivity within regular cannabis users before, during, and after a cannabis discontinuation protocol; researchers will also compare sleep, circadian phase, and light sensitivity between regular cannabis users and control non-cannabis users. Participants will: 1. Participate in a 1-week baseline period consisting of at-home monitoring (sleep diaries, actigraphy, EEG headband). 2. Participate in a 2-night lab visit consisting of circadian phase and light sensitivity assessment. 3. Participate in a 4-week cannabis discontinuation pro…
Eligibility
- Age range
- 18–25 years
- Sex
- All
- Healthy volunteers
- Yes
List the inclusion criteria: * Age 18-25 years * Physically and psychiatrically healthy, as determined by instruments described below * Cannabis-Using group only: Regular cannabis use, defined as "frequent" (6-29 days/month) or "daily" (daily) use over the past 3 months * Cannabis-Using group only: Willingness to discontinue cannabis for 4 weeks. * Control group only: No cannabis use in the past 3 months. Deny engaging in daily or near-daily cannabis use during the past year. No history of alcohol and/or substance use disorders. No current sleep disorders (including insomnia and delayed sleep…
Interventions
- BehavioralCannabis Discontinuation
Cannabis-using participants will participate in an orientation session with a clinician and asked to abstain from cannabis use for four weeks, using established procedures for abstinence monitoring and reinforcement.
Location
- Western Psychiatric Hospital (Thomas Detre Hall)Pittsburgh, Pennsylvania