Testing Oral Nicotine Pouches to Reduce Smoking-Related Cancer in Rural Appalachia

Summary

This clinical trial compares the use of oral nicotine pouches to nicotine replacement therapy, consisting of nicotine patches and lozenges, to reduce cigarette use in smokers living in rural Appalachia. The lung and oral cancers that plague Appalachia are fueled by cigarette smoking. Oral nicotine pouches which contain nicotine but no tobacco leaf, present a new opportunity to reduce cancer risk among Appalachian adults who smoke. Oral nicotine pouches and nicotine replacement therapy may work well to reduce cigarette use for smokers in rural Appalachia.

Description

Eligibility

Age range

21+ years

Sex

All

Healthy volunteers

Yes

Interventions

• Other
  Carbon Monoxide Measurement

  Undergo carbon monoxide measurement

• Other
  Nicotine Lozenge

  Use nicotine lozenge

• Other
  Oral Nicotine Pouch

  Use oral nicotine pouch

• Other
  Nicotine Patch

  Use nicotine patch

• Other
  Survey Administration

  measurements; data gathering

• Other
  Check-in Phone Calls

  Check-in phone calls to study participants

Location