Mayo Clinic
This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological mechanisms are significant for patient populations facing complex health challenges, such as those with cancer and neurodegenerative disease, and their caregivers. By measuring oxygen delivery to brain tissues and cerebrospinal fluid flow, this trial may help researchers investigate the potential benefits of respiratory training for patients with MS and cancer and their caregivers.
PRIMARY OBJECTIVE: I. To evaluate the immediate and long-term effects of improved respiratory function on local tissue oxygen delivery and cerebral circulation, by comparing control and training groups. SECONDARY OBJECTIVE: I. To identify key biological aspects of breathing related to brain health and mental well-being, our research explores how respiratory function can improve clinical symptoms related to fatigue and emotional states. EXPLORATORY OBJECTIVE: I. To establish a clinically applicable support tool that uses effective breathing practice to help patients, and their caregivers b…
Inclusion Criteria: * STUDY 1: Participants must be physically fit enough to perform light exercise. * STUDY 1: Should read and understand English well enough to consent, complete measures, and follow instructions. * STUDY 1: Must have access to a smartphone or tablet. * STUDY 2: Participants must be physically fit enough to perform light exercise. * STUDY 2: Cancer patients may have prostate cancer, neuroendocrine tumor, or brain cancer in any stage. * STUDY 2: The main focus is on pairs of cancer patients and their respective caregivers, but individual cancer patients or individual caregive…
Undergo blood sample collection
Participate in walking routines
Undergo MRI
Ancillary studies
Participate in breathing sessions
Arctuva estimate
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