Brigham and Women's Hospital
The goal of this study is to learn whether insufficient sleep affects glucose metabolism differently in healthy men and women.
Two-thirds of Americans report regularly obtaining an insufficient amount of sleep. Chronic sleep deficiency is associated with negative health consequences such as obesity, cardiovascular disease, diabetes, and metabolic syndrome. Laboratory studies have shown that sleep restriction reduces glucose tolerance in otherwise healthy adults, and it is now well established that sleep restriction decreases insulin sensitivity. However, there is a significant gap in the literature regarding how sex differences may drive disparate metabolic outcomes in men and women in response to sleep loss. Epidemi…
Inclusion Criteria: * Healthy adults with conventional sleep-wake timing * Non-smokers * Completion of medical, psychological, and sleep screening tests * Able to spend 5 consecutive days/nights in the laboratory on two separate occasions (total of 10 days/nights in the laboratory) * Women must have a recent history of regular menstrual cycles Exclusion Criteria: * History of neurological or psychiatric disorder * History of sleep disorder or regular use of sleep-promoting medication * Current prescription, herbal, or over-the-counter medication use including hormonal birth control * Travel…
Participants will be asked to sleep 4h/night
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