Evaluating Q-Collar Effects on Cerebrovascular Control in Response to Exercise
Spaulding Rehabilitation Hospital
Summary
The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are: 1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance? 2. How does the Q-Collar affect brain blood flow during exercise? Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise. Participants will: * Complete two study visits, each 1 to 4 weeks apart. * Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored. * Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.
Description
We are doing this research to improve our understanding of how a FDA-cleared device, called the Q-Collar, affects brain blood flow regulation both at rest and in response to exercise. Participants will be asked to complete two study visits over a period of 1 to 4 weeks. Each visit will involve identical assessments, with the Q-Collar worn during one session and not during the other. The order of the sessions will be randomly assigned. Each visit consists of three main tasks: Standing Test (approximately 10 minutes): Participants will perform a series of movements, standing up from a seated p…
Eligibility
- Age range
- 18–30 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * healthy individuals between the ages of 18 to 30 years old Exclusion Criteria: * History of concussion or other brain injury resulting in loss or alteration in consciousness or other change in cognition within 24 months of study visit * High cardiac risk according to the American College of Sports Medicine (ACSM)11 * Ongoing active treatment with a cardioactive drug * Inability to stand from a seated position unassisted * History of a neurologic disorder or neurosurgery intervention * Pregnancy * Any current, serious, chronic medical or psychiatric disease that in the…
Interventions
- DeviceQ30 Q-Collar
Participants will complete a series of tests (sit-to-stand, resistive breathing, and graded bike test) while wearing a Q-Collar.
- OtherNot wearing Q-Collar
Participants will undergo the same study procedures without wearing the Q-Collar.
Location
- Spaulding Rehabilitation HospitalCambridge, Massachusetts