Silent Brain Infarcts in Spontaneous Intracerebral Hemorrhage as a Prognostic Biomarker for Vascular Contributions to Cognitive Impairment and Dementia (VCID)

Summary

The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are * if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests Participants will undergo * cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH

Description

Eligibility

Age range

18–80 years

Sex

All

Healthy volunteers

No

Interventions

• Diagnostic Test
  MRI

  MRI during hospitalization and at 12 months post sICH

• Diagnostic Test
  Blood Draw

  Will occur during hospitalization and at 3, 6 and 12 months post sICH

• Diagnostic Test
  Cognitive Test

  Cognitive testing will occur during hospitalization and at 3, 6 and 12 months post sICH

Location