Interactions Between Delta-9-THC and CBD: A Controlled Human Drug-administration Study Probing a Harm Reduction Strategy

Inclusion Criteria: * Male or non-pregnant and non-lactating females aged 21-55 years * Report cannabis use 1-7 days per week over the month prior to screening * Not currently seeking treatment for their cannabis use * History of inhaled cannabis use * Have a Body Mass Index from 18.5 - 34 kg/m2 * Able to perform all study procedures * Must be using a contraceptive (hormonal or barrier methods) Exclusion Criteria: * Meeting DSM-V criteria for severe Cannabis Use disorder (CUD) or any substance use disorder other than nicotine, caffeine, mild or moderate CUD * Evidence of severe psychiatric…