Core Semantic Systems of the Human Brain
University of South Carolina
Summary
This study examines the time course of activation of the left anterior temporal lobe (ATL) during lexical processing using Transcranial Magnetic Stimulation (TMS).
Description
This study investigates the activation time of the anterior temporal lobe (ATL) region during lexical processing. Participants will perform three tasks: lexical decision, semantic decision (divided into noun and verb semantic decision), and number judgment. Lexical Decision Task: Participants will be shown words and pseudowords (e.g., excaid). Participants have to decide if the presented stimulus is a real word or a pseudoword. Semantic Decision Task: Participants will determine if the stimulus word refers to an action or an object that can be manipulated using the hand or arm. Half of the…
Eligibility
- Age range
- 18–40 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Participants must be within the ages of 18 to 40 * Native speakers of English Exclusion Criteria: * Potential participants with a clinically reported history of dementia, alcohol abuse, psychiatric or neurological disorders, traumatic brain injury, or extensive vision or hearing problems that prevents them from performing the tasks * Contraindication to TMS, determined by a standard TMS screening form * Contraindication to MRI, determined by a standard MRI screening form * Left handed participants
Interventions
- DeviceSingle-pulse TMS
A single pulse TMS is delivered at different time points when processing words or numbers.
Location
- Prisma Health RichlandColumbia, South Carolina