University of Illinois at Chicago
The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.
This is an exploratory, randomized, crossover-controlled feeding study of a 4-week Mediterranean Diet or usual diet control among 24 adults with sickle cell disease and chronic pain (30 will be recruited, with an estimated 24 participants completing the study).
Inclusion Criteria: * Sickle Cell Disease Diagnosis * Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for \> 6 months (based on a response of "Most days," "Every day," or "Some days" and not "Never" to the question "In the past 6 months, how often have you had pain?") * Ability to speak, read, write, and understand English * A Mediterranean Eating Pattern for Americans (MEPA-III) score \<13, indicating that they do not follow a Mediterranean diet. Exclusion Criteria: * Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks) * History of…
Mediterranean Diet foods will be provided for 4 weeks.
Participants will consume their typical at home-diet.
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