Breastmilk Composition in Response to a Bout of Exercise
Mayo Clinic
Summary
The purpose of this study is to unveil the mechanistic benefits of a bout of postpartum maternal exercise on infant health that are provided by breastmilk.
Description
The nutrients and antibodies in breastmilk promote infant growth, development, and immunity. Breastfed infants exhibit lower risk of adult-onset obesity and type 2 diabetes compared to formula-fed infants, and the composition of breastmilk is influenced by maternal factors such as obesity and type 2 diabetes, profoundly impacting its health benefits. While postpartum maternal exercise enhances infant health, its effects on breastmilk composition remain unknown, hindering our understanding of how postpartum exercise benefits breastfed infants.
Eligibility
- Age range
- 18–45 years
- Sex
- Female
- Healthy volunteers
- Yes
Exclusion Criteria: * Active coronary artery disease or heart failure. * Participation in a structured exercise program ≥ 1 day/week in the "inactive" subcohort or \< 3 days per week in the "active" subcohort. * A known medical condition that in the judgment of the investigator might interfere with the completion of the protocol such as the following examples: * Abnormal liver function test results (Transaminase \>2 times the upper limit of normal * Abnormal renal function test results (calculated GFR \<60 mL/min/1.73m2); * If on antihypertensive, thyroid, anti-depressant or lipid lowe…
Interventions
- OtherPre-Pregnancy BMI
Pre-pregnancy BMI between 18.5-24.99
- OtherPre-Pregnancy BMI
Pre-pregnancy BMI between 25-39.99
Location
- Mayo ClinicRochester, Minnesota