Wren Laboratories LLC
Endometriosis is a common disease that affects up to 10% of women of reproductive age. Diagnosis, however, is typically delayed (up to 12 years) and is usually made after surgery. A key unmet need therefore is an accurate biomarker that can be used to detect the disease early. This study is a prospective trial to identify candidate mRNA-markers which can be used to aid in the diagnosis of this disease. It is a discovery/validation study that will identify and confirm a gene expression panel that is specific for endometriosis and provides a non-invasive tool for future use.
Endometriosis is a common disease that affects up to 10% of women of reproductive age. Diagnosis, however, is typically delayed (up to 12 years) and is typically made after surgery. A key unmet need therefore is an accurate, non-invasive biomarker that can be used to detect the disease early. We hypothesize that endometriosis-related circulating gene expression can be identified using transcriptomic and bioinformatics approaches and used to construct an accurate diagnostic tool for this condition. The primary objective is to develop a gene signature that detects endometriosis. The hypothesis…
Inclusion Criteria: For the endometriosis cohort * a history of infertility more than 1 year * age 20-35 years * normal liver and kidney function, without gynaecological and other systemic disease Inclusion criteria for controls include normo-ovulatory history, aged between 20-35 years, who exhibit normal liver and kidney function, and do not have any systemic diseases including autoimmune disease. \- Exclusion Criteria: For the endometriosis cohort * polycystic ovary syndrome, hyperprolactinemia * severe cardiovascular system, liver, kidney, and hematopoietic system disease * autoimmun…
PCR assay for Endometriosis diagnosis
Arctuva estimate
Actual pay is set by the research site.
Verify or correct the compensation shown for this listing.