Incyte Corporation
This study will be conducted to evaluate the effect of food on the single-dose pharmacokinetics and a drug-drug interaction evaluation of itraconazole and carbamazepine on INCB123667 when administered orally to healthy adult participants.
Inclusion Criteria: * Ability to comprehend and willingness to sign a written ICF for the study. * Age 19 (in compliance with Nebraska state law) to 55 years, inclusive, at the time of signing the ICF. * Body mass index between 18.0 and 32.0 kg/m2, inclusive, at screening. Note: Only up to 25% of the participants may be enrolled with a BMI \> 30 to ≤ 32.0 kg/m2. * No clinically significant findings on screening evaluations (clinical, laboratory results \[with the exception of lipids\], and ECGs). * Ability to swallow and retain oral tablets. * Willingness to avoid pregnancy or fathering child…
single dose administered orally
Oral: Tablet
Oral; Tablet
Arctuva estimate
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