University of Arizona
This study is examining the effects of six weeks of inspiratory muscle strength training (IMST) on outcomes related to pulmonary hypertension. This study leverages previous cardiopulmonary exercise test (CPET) results and a pre-existing upcoming CPET to examine the effects of IMST on cardiopulmonary pressures and exercise tolerance and ability.
PH is a condition characterized by abnormally high blood pressure in the lungs (i.e., pulmonary arterial pressure), which impacts heart function and reduces exercise tolerance. This study will assess whether six weeks of a breathing exercise called IMST can improve heart and lung function as well as exercise capacity for individuals with PH. For this study, patients will be asked to perform IMST for the six weeks prior to their next scheduled clinical standard of care assessment of their PH. The goal of this study is to determine whether IMST reduces pulmonary arterial pressure and improves e…
Inclusion Criteria: * Diagnosed with PH defined by clinical guideline criteria * Must already be scheduled for a clinical assessment of their PH within 8 weeks of enrolling in the study. * Must have undergone an assessment of their PH in the last 18 months with no major changes in PH management or medication within that period. Exclusion Criteria: * Current smoker or have smoked in the last 10 years * Unable or unwilling to undergo routine functional testing of their PH (i.e., 6-minute walk distance). * Presence of significant cardiovascular or respiratory conditions other than PH, includin…
Participants will be asked to inhale against a resistance. This resistance will be set to \~55% of their maximal inspiratory ability. Participants will complete 5 sets of 6 breaths (30 total) a day for 5 days a week for 6 weeks.
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