Effects of Spirulina Supplementation on Mental Health in Healthy Adults
Arizona State University
Summary
Spirulina platensis is a form of cyanobacteria, a blue-green algae, and is a superfood most known for being rich in protein, vitamins and minerals, and healthful phytochemicals. Spirulina supports brain health through neuroprotection offered by its antioxidants, anti-inflammatory properties, and hormone regulation. The aim of this study is to supplement healthy adults from a campus community with 3g of spirulina, daily, for 8 weeks to improve mood and mental acuity in comparison to receiving a placebo.
Description
Spirulina is nutrient-dense with vitamins and minerals which provide antioxidants and anti-inflammatory mechanisms to help reduce oxidative stress and ROS activity. Preclinical studies have indicated Spirulina can reduce inflammatory cytokines, such as IL-1β, and reverse stress responses and oxidative damage in BDNF, nuclear factor erythroid 2-related factor (NRF2), and ultimately the phosphorylation of protein-kinase B (AKT), which promotes cell growth. In addition to these benefits, fatty acids, gamma-linolenic acid (GLA) and glycolipids, support gut health and the immune system. In combinat…
Eligibility
- Age range
- 16–65 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * healthy adults * ages 18-65 * no underlying chronic disease or acute conditions * no autoimmune conditions * do not consume alcohol in excess, smoke, use recreational drugs * does not follow restrictive diets * will be recruited from the ASU university campus. Exclusion Criteria: * not have been clinically diagnosed with depression * not taking antidepressants, anxiety, or stress medications, or any other medications * drugs, or supplements that could influence mental capacities * not pregnant or breastfeeding * not a competitive athlete
Interventions
- OtherSpirulina capsules
active intervention
- OtherPlacebo
no active ingredient
Location
- 850 PBCPhoenix, Arizona