Bacterial Responses to Enteric Alterations After Ketones
University of California, San Francisco
Summary
The goal of this observational study is to learn if a ketone ester can improve the content of the gut microbiome. The main questions it aims to answer are: * Does a ketone ester reduce age-related signatures in the gut microbiome? * What changes occur in the gut microbiome after consuming a ketone ester? Participants will: * Take a ketone ester every day for seven (7) days * Collect and ship stool samples within seven (7) days before, during, and within seven (7) days after the study period * Measure their ketone levels with a urine strip every day after having the drink * Answer questions about their typical diet on a normal day * Record their symptoms, if any arise
Eligibility
- Age range
- 18–40 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Subject is male or female, 18 to 40 years of age, inclusive, at Virtual Visit 1. * Subject has a self-reported BMI of 18.5 to 39.9 kg/m2 (inclusive) at Virtual Visit 1. * Subject is willing and able to comply with all study procedures including maintenance of habitual dietary intake, consumption of study product at specified intervals, written questionnaires including study log and beverage tolerability questionnaire (KETQ), habitual exercise and medication and supplement use. * Subject has an email address and internet access via computer, phone, or other device, and is…
Interventions
- Dietary SupplementExogenous ketone ester
25g Bis-octanoyl-(R)-1,3-butanediol (C8)
Location
- UCSF Wayne and Gladys Valley Center for VisionSan Francisco, California