A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa
Incyte Corporation
Summary
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in participants with hidradenitis suppurativa.
Eligibility
- Age range
- 12+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Diagnosis of HS for at least 6 months prior to screening visit. * Mild to moderate HS (Hurley I or II) with the following at both screening and baseline visits: * A total AN count of at least 4, with no draining tunnels AND * Affecting at least 2 distinct anatomical areas * Agreement to NOT use topical and systemic antibiotics for treatment of HS during the vehicle-controlled period. * Agreement to NOT use topical antiseptics, including washes and leave-on products on the areas affected by HS lesions during the vehicle-controlled period and Weeks 16 to 20 of the ext…
Interventions
- DrugRuxolitinib Cream
Ruxolitinib cream applied topically to the affected area as a thin film twice daily.
- DrugVehicle Cream
Matching vehicle cream applied topically to the affected area as a thin film twice daily.
Locations (107)
- Investigative Site US257Birmingham, Alabama
- Investigative Site US218Birmingham, Alabama
- Investigative Site US239Montgomery, Alabama
- Investigative Site US215Phoenix, Arizona
- Investigative Site US261Phoenix, Arizona
- Investigative Site US240Tucson, Arizona