A Novel Method for Determination of Thromboembolic Stroke Origin
Atlantic Health System
Summary
Rupture of vulnerable carotid, vertebral, and intracranial arterial plaques results in thromboembolic stroke. Identification of these culprit lesions is an important component of post-stroke care. This study seeks to test the feasibility of NaF PET-CT to detect these plaques and alter patient care. Prior studies have shown a high degree of correlation between NaF PET+ lesions and high-risk plaque features on high resolution MRI, including mirocalcification, necrosis, and ulceration.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 18 years of age or older with a non-cardiogenic thromboembolic stroke in the past 14 days. Exclusion Criteria: Less than 18 years of age, any other kind of stroke, not clinically stable to undergo PET-CT
Interventions
- DrugNaF PET-CT
Following a non-cardiogenic thromboembolic stroke, patients will undergo NaF PET-CT imaging to identify the culprit plaque and any other vulnerable plaques at high risk for rupture
Location
- Overlook Medical CenterSummit, New Jersey