Abramson Cancer Center at Penn Medicine
The goal of this RENEW-EVAL project is to understand the potential barriers to implementation of the RENEW intervention into the routine clinical care of patients with a hematological malignancy.
The RENEW clinical intervention is designed to evaluate the impact of a comprehensive beta lactam (BL) allergy delabeling intervention on clinical outcomes among patients hospitalized with a hematologic malignancy (HM). HM patients are at a high risk of infection-related complications but are limited to antibiotic therapy based on self-reported allergies. The RENEW intervention will test the impact of a pharmacist-led BL allergy delabeling intervention on clinical outcomes and antibiotic use in hospitalized patients with HM. The implementation of clinical interventions are often affected by n…
Inclusion Criteria: Patient participants: * a diagnosis of a hematologic malignancy (lymphoma, leukemia, myeloma) * a prior label applied to their medical record to indicate a beta lactam allergy * hospitalized as an inpatient to an oncology service at the time the study is conducted Clinician participants: * member of the primary inpatient care team Exclusion Criteria: Patient participants: * meet one of the exclusionary criteria for the RENEW clinical intervention Clinician participants: * no exclusions
Interviews designed to obtain information about patient reasons for enrolling or declining participation in the RENEW Intervention
Survey which will incorporate a series of closed-ended questions eliciting attitudes about the feasibility and acceptability of the intervention, allergy delabeling and future BL antibiotic use
Observations designed to identify communication and contextual barriers to the implementation of RENEW
Survey instruments will measure knowledge,attitudes, and practices surrounding allergy delabeling and antibiotic stewardship in patients with HM and perceptions of the feasibility and acceptability of the RENEW intervention
Interviews designed to obtain information from clinicians about their perception of the implementation of the RENEW intervention
Arctuva estimate
Actual pay is set by the research site.
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