University of Rochester
Atrial fibrillation (AF) is the most common type of irregular heartbeat doctors see. People with AF sometimes have a procedure called an ablation to help get their heart back into a normal rhythm. However, this treatment doesn't always work. This study is looking at whether adding an extra step to the usual ablation-specifically treating another area of the heart called the left atrial (LA) posterior wall-can help people feel better overall, compared to just repeating the standard pulmonary vein isolation ablation procedure.
Inclusion Criteria * Age ≥ 18 years on date of consent * One prior PVI ablation procedure \> 3 months prior for persistent AF * Recurrent paroxysmal or persistent symptomatic AF confirmed on ECG despite prior PVI * Eligible for repeat ablation procedure * Willingness to comply with all post-procedural follow-up requirements and to sign informed consent Exclusion Criteria * Inability to undergo AF catheter ablation (e.g., presence of a left atrial thrombus) * Prior ablation that included non-PVI LA ablation, or more than one prior PVI ablation procedure for persistent AF * Prior surgical abl…
A doctor inserts a thin, flexible tube (called a catheter) through a blood vessel, usually in the groin, and guides it to the heart. Once the catheter is in place, the doctor uses pulsed field electroporation, heat (radiofrequency) or cold (cryoablation) to create small scars in the area where the pulmonary veins connect to the left atrium of the heart. These scars block the faulty electrical signals that cause AF, helping the heart maintain a normal rhythm.
PVI with an additional step where the doctor also isolates the back wall (posterior wall) of the left atrium.
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