Ischemic Preconditioning in Osteoarthritis and Back Pain
University of Illinois at Chicago
Summary
We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.
Eligibility
- Age range
- 50+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Reported Knee Pain using ACR Criteria * Reported Back Pain using ODI Criteria \> 12 * Ability to walk for at least 3 minutes without the use of aids * Ability to provide written informed consent Exclusion Criteria: * Younger than 50 years old * History of Knee or Hip Replacements * History of steroid injection within the previous 6 months * Presence of neuromuscular joint condition that affects lower extremity function * History of blood clots in the leg or any condition in which compression of the thigh is contraindicated * History of heart failure or thrombosis * All…
Interventions
- DeviceIschemic Preconditioning
The intervention arm will include full blood flow occlusion in one thigh for 5 minutes followed by 5 minutes of reperfusion for a cycle of 50 minutes.
- DeviceSham Intervention
This intervention includes 25mmHg of pressure, which is not sufficient for blodo flow occlusion.
Location
- Human and Sport Performance LabChicago, Illinois