Improving Recovery in Older ICU Survivors: Evaluation of Swallowing Dysfunction and Aspiration Risk
Vanderbilt University Medical Center
Summary
Post-intensive care syndrome (PICS), which consists of physical, cognitive, and psychosocial problems, is a pervasive complication for older intensive care unit (ICU) survivors and contributes to detrimental health outcomes and significant reductions in quality of life. Yet, little is known about the relationship between PICS, swallowing difficulties (dysphagia), and other ICU-related negative outcomes such as frailty and Alzheimer's Disease and Related Dementias (ADRD). The primary purpose of this research study is to determine the prevalence and severity of dysphagia, risk factors for dysphagia development, recovery patterns of dysphagia over time, and the impact of dysphagia on health outcomes, quality of life, and care partner burden in adult ICU survivors with PICS.
Description
This study will involve one in-person research visit for community dwelling adults and two research visits for critically ill adults (one in the ICU, one 3-months post-hospital discharge) that will last approximately 1 hour and will consist of a screening, cough testing, swallow function testing, assessments of hand grip and tongue strength, and completion of questionnaires. Caregivers of ICU survivors will complete questionnaires at the 3-month follow up visit.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion criteria community-dwelling adults: 1. adult ≥18 years old 2. no prior history of neurological diseases or respiratory diseases 3. no prior history of head and neck surgery/head and neck cancer/radiation to head and neck region 4. no prior history of dysphagia. Exclusion criteria community-dwelling adults: 1. \<18 years old 2. neurological disease or respiratory disease diagnosis 3. history of head and neck cancer/surgery to the head and neck region 4. history of dysphagia. Inclusion criteria critically-ill adults: 1. adult ≥ 18 years old 2. ICU patients requiring monitoring or…
Location
- Vanderbilt University Medical CenterNashville, Tennessee