Ovarian Platelet-Rich Plasma (oPRP) Injections Improvement In IVF Patients Based On Time-Lapse Incubator Culture for Automated Tracking and AI for Embryo Quality Assessment : A Non-Randomized Propsective Self-Controlled Interventional Study
Generation Next Fertility
Summary
Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.
Description
. oPRP Treatment \& Second IVF Cycle (Study Cycle) * Following the first IVF cycle, patients will undergo their first oPRP injection: * Timing: 1-2 weeks after the onset of the next menstrual cycle. * Procedure: Under IV sedation, a patient's autologous PRP will be prepared and injected directly into both ovaries under transvaginal ultrasound guidance. * Second IVF Cycle (oPRP Study Cycle) * The same ovarian stimulation protocol will be used for consistency. * A second oPRP injection will be performed on stimulation days 2-5 to enhance folliculogenesis. * Ovulation will be trigger…
Eligibility
- Age range
- 18–47 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * No none contraindications to IVF or PRP treatment * Adequate ovarian reserves and AMH level * Willingness to undergo two IVF cycles and oPRP treatment Exclusion Criteria: * Anovulation due to menopause or perimenopause * Any health conditions that are contraindicated for IVF or oPRP treatment
Interventions
- ProcedureOvarian Platelet-rich plasma (PRP) injections
This is a procedure that our patients receive at our clinic. We want to use the AI software to evaluate embryo development before and after treatment to see if there is a difference in embryo quality after PRP treatment within the same patient.
Location
- Generation Next FertilityNew York, New York