University of Michigan
This study will examine whether the use of synthetic carbon apatite bone graft material will lead to more bone formation compared to human derived allograft and bovine derived xenograft material.
Bone grafts are commonly placed to increase the amount of bone right after tooth extraction and prepare the site for future dental implant placement. 45 patients requiring a tooth extraction will be recruited and randomized to receive either allograft, xenograft, or synthetic bone grafting.
Inclusion criteria: * Age between 20 and 80 years old * Patients requiring tooth extraction (incisors, canines, and premolars) due to caries, periodontal disease, tooth fracture, or unrestorable condition. * Extraction sockets must be infection-free with dehiscence less than 5mm. * Patients interested in implant placement after tooth extraction. Exclusion criteria: * Known allergies or hypersensitivities to medications related to the study (e.g., chlorhexidine) * Hematologic disorders or blood dyscrasias. * Active infectious diseases. * Liver or kidney dysfunction/failure. * Uncontrolled di…
After tooth extraction, the socket will be filled with a collagen plug and bone graft.
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