University of Michigan
This study will examine whether using PRF and your age are going to affect the healing and regeneration benefits gained from PRF.
Platelet-rich fibrin (PRF) is commonly used to enhance gum tissue healing and reducing pain after tooth extraction and before placing a dental implant. 44 patients requiring a tooth extraction will be recruited and randomized to receive a collagen plug with or without platelet-rich fibrin.
Inclusion Criteria: 1. Age range: 20 to 80 years. 2. Patients must require tooth extraction (molars) as a result of caries, periodontal disease, tooth fracture or deemed unrestorable. 3. Non-infected sockets with intact buccal bone (≥1.5 mm in thickness measured through calipers) 4. Patients interested in implant placement following tooth extraction. Exclusion Criteria: 1. Allergies or hypersensitivities to study related medications. 2. Hematologic disorders/blood dyscrasias. 3. Active infectious diseases of any kind. 4. Liver or kidney dysfunction/failure. 5. Uncontrolled diabetes (HbA1c \…
After tooth extraction, the extraction socket will be filled with a collagen plug in one group or a platelet-rich fibrin plug in the other.
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