EXERT-BCHC: Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Summary
This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 cluster sets and double training) to assess changes in VO2 max, muscle mass, and fat mass.
Eligibility
- Age range
- 20–89 years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: 1. Age 20-89 years 2. Women prescribed exercise as a Standard of Care 3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast 4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. 5. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed. 6. Women with \> 6 months of resistance training experience under expert guidance by a CSCS Exclusion Cri…
Interventions
- Other6-12-25 Training Regimen
A conditioning regimen involving three exercises performed consecutively with minimal rest. Includes 4-6 repetitions at 4-0-1-0 tempo, 10-12 repetitions at 3-0-1-0 tempo, and 20-25 repetitions at 2-0-1-0 tempo.
- Other8x8 Training Regimen
A conditioning regimen optimizing high volume with short rest periods. Six exercises are performed consecutively with a 2-0-1-0 tempo and no rest between sets.
- Other5/5/5 Cluster Set Training Regimen
A hypertrophy regimen where an individual performs 5 repetitions at a tempo of 4 seconds during the eccentric movement of the exercise, while performing the concentric motion in 1 second then resting for 20 seconds and repeating the sequence two additional times to total three clusters of 5 repetitions.
- OtherDouble Training Regimen
A hypertrophy regimen adding an additional set of lesser repetitions for a specified exercise at the end of a tri-set of exercises.
Location
- Allegheny General HospitalPittsburgh, Pennsylvania