University of California, San Francisco
Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.
Inclusion Criteria: * Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography * Access to digital device and internet at home * Ability to provide written informed consent before any study-related activities * Ability to remain in study for at least 3 months Exclusion Criteria: * Allergy to milk protein * On hemodialysis * No English language proficiency * Presence of condition or abnormality that in opinion of the Investigator will compromise safety of the patient or quality of the data * Concomitant severe underlying systemic illness tha…
HEAL-ME is a digital prehabilitation app that provides semi-guided nutrition/exercise prehabilitation
Patients will take 5g creatine supplementation daily for 13 weeks
Patients will take 35g whey protein supplementation daily
Patients will be administered daily placebo supplementation.
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