Gut-Brain Neural Coupling in Spinal Cord Injury
University of Miami
Summary
The purpose of this research is to determine the effects of food on brain and stomach activity in persons with and without spinal cord injury (SCI).
Eligibility
- Age range
- 18–70 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria, SCI and Controls * Adults, 18 to 70 years of age. * Sex, male or female. * Weight-stable (±3 kg) for the preceding 3 months (self-report). * Physically inactive adults not meeting weekly activity guidelines (\<150 min/week) for the preceding 3 months (self-report). * Fluent in written and spoken English. Exclusion Criteria, SCI and Controls * Do not meet the inclusion criteria. * Current/regular smoker (defined by Center for Disease Control (CDC)/ National Institute of Health (NIH) as an adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes…
Interventions
- OtherPreload condition
Participants will consume a fixed compulsory preload meal of Campbell's Tomato soup (\~300 grams) 30 minutes after the baseline assessments. Fifteen minutes after consuming the preload meal, participants will receive the ad libitum test meal, consisting of a pre-weighed serving of Stouffer's Macaroni and Cheese (\~700 g).The pre-load condition will be completed at only one of two visits. Participation will be up to 2 weeks with the visits separated by up to 2 weeks. Duration for the pre-load condition visit will be up to 6 hours
- OtherAd-libitum control condition
Participants will only consume the ad libitum test meal, which consists of a pre-weighted serving of Stouffer's Macaroni and Cheese (\~700 g). The ad-libitum meal will be consumed at both visits. Participation will be up to 2 weeks with the visits separated by up to 2 weeks. The ad-libitum control condition visit will take up to 2 hours.
Location
- University of Miami - Miami Project to Cure ParalysisMiami, Florida