Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

University of California, Irvine

Summary

This is a single-armed screening research study which screens immediate family member of lung cancer patients with a driver mutation to see if lung cancer can be inherited and whether researchers can find lung cancer early. Immediate family members of lung cancer patients will be 40-80 years old and screened using a low dose CT scan.

Eligibility

Age range: 18–80 years
Sex: All
Healthy volunteers: No

Detailed criteria

Cohort A: Inclusion Criteria: * Current diagnosis of lung cancer with a driver mutation. * Known driver mutation (e.g. via NGS, PCR, IHC, FISH, RT-PCR etc.) * Able and willing to give informed consent. * Able and willing to complete the screening questionnaire. Cohort A: Exclusion Criteria: * There are no exclusion criteria for Cohort A. Cohort B: Inclusion Criteria: * Age 40 - 80. * Must have a first degree relative (mother, father, sibling, biological child) eligible for Cohort A. Note: Multiple first degree relatives of a Cohort A eligible participant may be approached for participa…

Interventions

Diagnostic Test
Low Dose CT Scan
Completed once after screening and eligibility is confirmed.

Location

Chao Family Comprehensive Cancer Center University of California, Irvine
Orange, California
ucstudy@uci.edu 877-827-8839

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

Summary

Eligibility

Interventions

Location

Compensation

Run this study?

Details

Conditions