Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer
University of California, Irvine
Summary
This is a single-armed screening research study which screens immediate family member of lung cancer patients with a driver mutation to see if lung cancer can be inherited and whether researchers can find lung cancer early. Immediate family members of lung cancer patients will be 40-80 years old and screened using a low dose CT scan.
Eligibility
- Age range
- 18–80 years
- Sex
- All
- Healthy volunteers
- No
Cohort A: Inclusion Criteria: * Current diagnosis of lung cancer with a driver mutation. * Known driver mutation (e.g. via NGS, PCR, IHC, FISH, RT-PCR etc.) * Able and willing to give informed consent. * Able and willing to complete the screening questionnaire. Cohort A: Exclusion Criteria: * There are no exclusion criteria for Cohort A. Cohort B: Inclusion Criteria: * Age 40 - 80. * Must have a first degree relative (mother, father, sibling, biological child) eligible for Cohort A. Note: Multiple first degree relatives of a Cohort A eligible participant may be approached for participa…
Interventions
- Diagnostic TestLow Dose CT Scan
Completed once after screening and eligibility is confirmed.
Location
- Chao Family Comprehensive Cancer Center University of California, IrvineOrange, California