Curcumin and Astaxanthin for Lowering Triglyceride Readings and Inflammation
Medinutra LLC
Summary
Two dietary supplements are each being compared to a placebo for the ability to help maintain triglycerides in the normal range. The subjects will be adult men and women with moderately high TG values. Serum triglycerides will be measured before and after 6 weeks of taking 1 capsule per day of either Longvida Curcumin, astaxanthin, or a placebo. A few side blood analysis will also be done. These measures are relevant to low level inflammation.
Description
Background Moderately high readings for serum TG have been thought to place many people at risk for cardiovascular disease (CVD) and other problems. However, for a few years, doubts were expressed about high TG as an independent risk factor for CVD and maybe other problems in most people. More recently, the tide has begun to turn back due to new studies and new attention to old studies. Now, TG readings are again being thought to affect vulnerability to CVD, fatty liver, high blood sugar, and other problems including general inflammation. Some of these studies have shown evidence that TG effec…
Eligibility
- Age range
- 21–59 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Triglyceride reading of 140-250 mg/dL * Age 21-59 Exclusion Criteria: * Uncontrolled diabetes * Hypothyroidism or other hormonal problems that have not stabilized * Any liver diseases being actively treated * Cancer * Renal dialysis use * Rheumatoid arthritis and related issues like lupus * Inflammatory bowel disease * Smoking * Low blood pressure * Having more than 5 alcoholic drinks per week * Extreme obesity (BMI over 37) * Pregnancy or lactation
Interventions
- Dietary SupplementCurcumin (Longvida™)
1 capsule per day at a usual curcumin dose for this particular product (80 mg curcumin)
- Dietary SupplementHalf Dose Curcumin (Longvida™)
1 capsule per day at half the usual curcumin dose for this particular product (40 mg curcumin as the half dose)
- Dietary SupplementAstaxanthin
1 capsule per day at a usual astaxanthin dose (12 mg)
- OtherPlacebo Control
Subject will get 1 capsule per day of a small amount of cellulose
Location
- Medinutra LLCDublin, Ohio