Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer
University of Southern California
Summary
This study assesses breast cancer screening adherence for women at moderately increased risk for developing breast cancer based on gene mutation status or empiric risk model estimates. It also seeks to determine facilitators and barriers to screening.
Description
PRIMARY OBJECTIVE: I. Among women without a history of breast cancer: to compare women with moderate risk breast cancer gene mutations (Mutation Carrier Group) to women with a 20-40% empiric lifetime risk of breast cancer (Empiric Risk Group) in terms of how likely they are to undergo recommended breast MRI screening. OUTLINE: This is an observational study. Patients complete a questionnaire and have their medical records reviewed on study.
Eligibility
- Age range
- 30–75 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * \* \>= 30 years * =\< 75 years * Women with either: * Genetic test results showing moderately increased breast cancer risk due to a pathogenic/likely pathogenic variant in ATM, CHEK2, BARD1, RAD51C, or RAD51D (Mutation carrier group) OR * Calculated lifetime breast cancer risk estimates between 20% and 40% according to the Tyrer-Cuzick V8.0B empiric risk model (Empiric risk group) * Patients provided breast cancer risk assessments by genetic counselors at USC Norris or LA General Hospital beginning in 2021 and at least 12 months ago * Women recommended…
Interventions
- OtherNon-Interventional Study
Non-interventional study
Locations (2)
- Los Angeles General Medical CenterLos Angeles, California
- USC / Norris Comprehensive Cancer CenterLos Angeles, California