Economic Evaluation of Managing Epilepsy Well (MEW) Network Epilepsy Self-Management Programs
NYU Langone Health
Summary
The investigators will conduct two-arm randomized controlled trials (RCTs) comparing effects of UPLIFT vs. enhanced usual care and PACES vs. enhanced usual care, respectively, on quality of life, depressive symptoms and seizures over 12 months in NYU patients with epilepsy.
Description
UPLIFT and PACES are two evidence-based epilepsy self-management programs whose adoption and impact are limited by the lack of sustainable funding models. The investigators will conduct an economic evaluation of these programs using data from completed and new trials in both healthcare and community settings. The investigators will conduct two parallel RCTs to compare effects of UPLIFT vs. enhanced usual care, and separately, PACES vs. enhanced usual care. Outcome data including patient-reported outcomes and costs will be aligned across the two trials and community implementation and collec…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adults (≥18 years) * English-speaking (UPLIFT and PACES) or Spanish-speaking (UPLIFT only). * Diagnosed with epilepsy for at least one year * Able to understand the informed consent and provide consent * Elevated depressive symptoms - Patient Health Questionnaire-9 (PHQ-9) score ≥10; applies to UPLIFT only Exclusion Criteria: * Severe depressive symptoms (score of ≥20 on PHQ-9) * Active suicidal ideation (score of ≥1 on PHQ-9 item #9 or otherwise reported during screening) * Active psychotic disorder (psychiatric diagnosis and/or antipsychotic medications in the electr…
Interventions
- BehavioralUPLIFT
UPLIFT is an 8-week epilepsy self-management programs delivered to small groups of people with epilepsy (PWE) by Webex. UPLIFT is focused on self-management of depressive symptoms. Each weekly session is 1 hour long and is comprised of a check-in period, teaching on the week's topic, group discussion, a skill-building exercise and a home practice assignment.
- BehavioralPACES
PACES is an 8-week epilepsy self-management programs delivered to small groups of people with epilepsy (PWE) by Webex. PACES focuses on general epilepsy self-management. Each weekly session is 1 hour long and is comprised of a check-in period, teaching on the week's topic, group discussion, a skill-building exercise and a home practice assignment.
- BehavioralEnhanced Usual Care
Participants receive referrals to local epilepsy support groups.
Locations (2)
- NYU Langone Health - NYU Langone Hospital-BrooklynBrooklyn, New York
- NYU Langone Health - NYU Comprehensive Epilepsy CenterNew York, New York