The Influence of Mango-Derived Intestinal Microbial Metabolites on Gut Permeability, Inflammation, and Cardiometabolic Health Markers in Hispanic/Latino Adolescents
University of California, Davis
Summary
Mangos contain a number of nutrients that may improve gut and metabolic health. The purpose of this research is to see how eating mangos every day for 4 weeks instead of snacks high in calories and low in nutrients such as cookies, crackers, chips, and candy can impact adolescent health.
Description
This study will record the functional and metabolic effects of daily mango intake, incorporated into the habitual diets of Hispanic/Latino adolescent children. This racial group is considered the most significant minority in the US, accounting for 19.1% of the population. The proposed study design allows for comparing baseline metabolic and physiological function to the real-world situation of adding a new snack food to a child in the major minority group in the US habitual diet. Moreover, the study design will allow the assessment of dietary changes in an understudied population at increased…
Eligibility
- Age range
- 12–19 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * \- Male or Female 12-19 years old * BMI ≥ 85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html) * Self-reported Hispanic/Latino * Subject is willing and able to comply with the study protocols * Subject is willing to consume the test products * Female-specific criteria: if menstruating, eumenorrheic (regular monthly menstrual cycles of 25-30-days in length) * Access to a smartphone or tablet at least 1x / day and willing to take pictures associated with the products to be consumed in the study Exclusion Criteria: * \- Reported food allergies…
Interventions
- OtherAtaulfo mango
4 weeks of Ataulfo mango intake
Location
- Academic Surge; Ragle Human Nutrition Research CenterDavis, California