Mechanisms of Visual Restoration After Occipital Stroke (MOVROS)
University of Rochester
Summary
This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how visual training impacts the function of the residual visual system to restore perception.
Eligibility
- Age range
- 21–80 years
- Sex
- All
- Healthy volunteers
- Yes
Cortically Blind Subjects (n=50) Inclusion: * Subjects between 21 and 80 years of age * Subjects must be residents of the United States or Canada * Subjects must exhibit unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 80 years (verified by MRI and/or CT scans) * Subjects with reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey, MAIA, Goldmann, and/or equivalent perimetry. This deficit must be large enough to enclose a 5-deg diameter visual stimulus. * S…
Interventions
- Diagnostic TestMRI
Functional MRI scan
Location
- University of RochesterRochester, New York