Dietary Iron Requirements in US Adults
Pennington Biomedical Research Center
Summary
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the iron isotope dilution technique. Following administration and equilibration of a stable iron isotope, participants will be followed for a 12 week study period. Blood will be collected every 4 weeks and the isotopic composition will be determined. Results will help update dietary iron guidelines making sure they better match the specific needs of the US population.
Eligibility
- Age range
- 18–50 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Males and premenopausal females age 18-50 y * Previously participated in an iron stable isotope study or willing to consume an oral stable iron isotope and undergo a one-year equilibration period * Willing to refrain from iron-containing supplements for the duration of the study * Willing to refrain from tobacco smoking for the duration of the study * Have not donated blood 3 months prior to the start of the study and willing to refrain from donating blood for the duration of the study * Willing to have blood stored for future use * Able and willing to comply with study…
Interventions
- OtherStable iron isotope
Stable iron isotopes will be used to determine iron requirements.
Locations (2)
- LSU Pennington Biomedical Research CenterBaton Rouge, Louisiana
- Cornell UniversityIthaca, New York