An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for PPOS
Urmila DIwekar
Summary
A clinical trial will determine the effectiveness of using the Opt-IVF decision support tool for each patient's personalized and optimal drug dosage profile in the United States.
Description
This will be a two-arm randomized clinical trial involving more than 100 patients; one arm will undergo superovulation using dosages predicted by the decision support tool, while the other will undergo the current standard treatment. The research question is whether outcomes of patient dosage treatment using Opt-IVF are better or similar to the current practice. We will compare the outcomes of the two groups of patients in terms of the numbers and percentage of mature follicles retrieved at the end of each cycle, total FSH and HMG dosages used, and the number of required testing days for that…
Eligibility
- Age range
- 20–50 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * infertile women Exclusion Criteria: All female patients who will not undergo IVF or whose cycles will be converted to IUI. Male patients will not be enrolled in this study. No donor cycles.
Interventions
- Combination ProductOpt-IVF
Opt-IVF provides optimized dosage profile for each patient
- OtherControl
Physicians will decide the dosage for each day for patients
Locations (2)
- Positivf FertilityHouston, Texas
- Positivf FertilitySan Antonio, Texas